2003 April O'Neil Motivational.

She's got a nice womanly looking design, was a scientist rather than a reporter, gets damsel'd far less frequently than other incarnations, can hold her own in a fight despite not having Ninjitsu training, and has Veronica Taylor's lovely voice too! Sure the almost Joker-esque color scheme that she had for most of the series was bizarre, but even that kinda grows on you after a while of getting used to it. xD All in all, coolest April EVER!